The Affective Dimension of Pain Appears to Be Determinant within a Pain-Insomnia-Anxiety Pathological Loop in Fibromyalgia: A Case-Control Study.

Lliure-Naima Mory Daniel de Oliveira FernandesChristian ManciniMichael Mouthon Joelle Nsimire Chabwine

Published in: Journal of clinical medicine (2022)

Discriminating between the sensory and affective pain components in FM patients disclosed a pathological loop, with a key role of affective pain; high ongoing pain acted as an amplifier of symptoms interaction. This unraveled the interplay between three of most cardinal FM symptoms; these results contribute to better understand FM determinants and pathology and could help in orienting therapeutic strategies.

Keyphrases

chronic pain
pain management
neuropathic pain
bipolar disorder
sleep quality
end stage renal disease
chronic kidney disease
newly diagnosed
transcription factor
ejection fraction
spinal cord
postoperative pain
prognostic factors
depressive symptoms
physical activity
patient reported