The comparison of serum TGF-beta levels and associated polymorphisms in patients with coronary artery ectasia and normal coronary artery.
Ozgur Selim SerGökhan ÇetinkalOnur KiliçarslanYalçın DalgıçServet BatitKudret KeskinGulçin ÖzkaraEzgi Irmak AslanHülya Yilmaz AydoğanAhmet YıldızZerrin YiğitPublished in: The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology (2021)
Our findings suggest that lower serum TGF-β1 levels are associated with an increased risk for CAE development and that TGF-β1 polymorphisms exert a protective effect. Furthermore, TGF-β1 rs1800470 G allele carriers were shown to have higher TGF-β1 levels in the CAE group. This suggests that having the G allele in the TGF-β1 rs1800470 polymorphism could prevent CAE development.