Autocatalytic Synthesis of Thioesters via Thiocarbonylation of gem-Difluoroalkenes.

Herein, we report a new method for the synthesis of acyethanethioates via thiocarbonylation of gem-difluoroalkenes with thiols. This reaction provides a new pathway to prepare thioesters under mild conditions without the use of any additives. Mechanistic studies revealed that in situ generated HF facilitated the C-F bond cleavage in an autocatalytic manner.