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Secondary haemophagocytic lymphohistiocytosis in COVID-19: correlation of the autopsy findings of bone marrow haemophagocytosis with HScore.

Claudia Núñez-TorrónAna Ferrer-GómezEsther Moreno MorenoBelen Pérez-MiesJesús VillarrubiaSandra ChamorroJavier López-JiménezJ PalaciosMiguel Piris-VillaespesaMónica García-Cosío
Published in: Journal of clinical pathology (2021)
Our results support the recommendation of some authors to use the HScore in patients with severe COVID-19 in order to identify those who could benefit from immunosuppressive therapies. The presence of haemophagocytosis in bone marrow tissue, despite not being a specific finding, has proved to be a very useful tool in our study to identify these patients.
Keyphrases
  • bone marrow
  • coronavirus disease
  • sars cov
  • end stage renal disease
  • mesenchymal stem cells
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • peritoneal dialysis
  • patient reported outcomes