Alkaline Earth Metal-Mediated Highly Iso-selective Ring-Opening Polymerization of rac-Lactide.

Alkaline earth (Ae) metal complexes of the aminophosphine borane ligand are highly active and iso-selective catalysts for the ring-opening polymerization (ROP) of rac-lactide (LA). The polymerization reactions are well controlled and produce polylactides with molecular weights that are precise and narrowly distributed. Kinetic studies reveal that the ROP of rac-LA catalyzed by all Ae metal complexes had a first-order dependency on LA concentration as well as catalyst concentration. A plausible reaction mechanism for Ae metal complex-mediated ROP of rac-LA is discussed, based on controlled kinetic experiments and molecular chain mobility.