Rectal organoid morphology analysis (ROMA) as a novel physiological assay for diagnostic classification in cystic fibrosis.

Senne Cuyx Anabela Santo RamalhoSteffen FieuwsNikky CorthoutMarijke ProesmansMieke BoonKaline ArnautsMarianne S CarlonSebastian MunckLieven DupontKris De BoeckFrançois Vermeulennull null

Published in: Thorax (2024)

ROMA provides additional information to support a CF diagnosis when SCC and genetics are insufficient for diagnostic classification. ROMA is standardised and can be centralised, allowing future inclusion in the diagnostic work-up as first-choice physiological assay in case of an unclear diagnosis.

Keyphrases

cystic fibrosis
machine learning
deep learning
high throughput
lung function
rectal cancer