Relationship between vemurafenib plasma concentrations and survival outcomes in patients with advanced melanoma.

Ganessan KichenadasseJim Henry HughesJohn O MinersArduino A MangoniAndrew RowlandAshley M HopkinsMichael J Sorich

Published in: Cancer chemotherapy and pharmacology (2019)

A plasma vemurafenib Css,min threshold of 50 mg/L is strongly associated with survival outcomes in patients with advanced melanoma. This new threshold needs to be validated prospectively in future studies.

Keyphrases

skin cancer
current status