Oxaliplatin-induced thrombotic microangiopathy: a case report.
Rhea SaadAudra HannunSally TemrazAntoine FinianosRony M ZeennyPublished in: Journal of medical case reports (2022)
Our case confirms the risk of hemolytic-uremic syndrome as a rare and life-threatening complication of oxaliplatin-based chemotherapy. A dose-dependent, drug-induced toxicity mechanism is suggested. Physicians need to maintain a high level of clinical suspicion to diagnose and treat this acute life-threatening disorder.
Keyphrases
- drug induced
- liver injury
- primary care
- oxidative stress
- adverse drug
- case report
- locally advanced
- liver failure
- squamous cell carcinoma
- radiation therapy
- intensive care unit
- diabetic rats
- endothelial cells
- respiratory failure
- acute respiratory distress syndrome
- hepatitis b virus
- aortic dissection
- chemotherapy induced
- electronic health record