R-Hexitronic acid, a new tetronic acid derivative isolated from a soil fungus FG9RK.
Kenneth G NgwokeDina H El-KashefGeorgios DaletosElena AncheevaZhen LiuFestus B C OkoyeCharles O EsimonePeter ProkschPublished in: Natural product research (2020)
A new tetronic acid derivative (1) together with terrestric acid (2), a known metabolite of Penicillium species, was isolated from the soil fungus, FG9RK following fermentation on solid rice medium. The structure of 1 was elucidated by one- and two-dimensional NMR and MS measurements. The absolute configuration of the oxygenated carbon in the side chain of 1 was identified as S by converting the compound into its Mosher ester whereas the absolute configuration of the lactone ring was deduced based on biogenetic considerations and comparison with 2.