Influence of an SGLT2 inhibitor, tofogliflozin, on the resting heart rate in relation to adipose tissue insulin resistance.

T NojimaY MatsubayashiAlkihiro YoshidaH SuganamiT AbeM IshizawaK FujiharaS TanakaK KakuHirohito Sone

Published in: Diabetic medicine : a journal of the British Diabetic Association (2020)

Tofogliflozin corrected resting heart rate levels in accordance with baseline levels. Correction of high resting heart rates may be attributed to improved adipose tissue insulin resistance, leading to correction of hyperinsulinaemia.

Keyphrases

heart rate
insulin resistance
adipose tissue
heart rate variability
high fat diet
blood pressure
polycystic ovary syndrome
metabolic syndrome
skeletal muscle
high fat diet induced
heart failure
atrial fibrillation
weight loss