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Tensor-conductance model for reducing the computational artifact in target tissue for low-frequency dosimetry.

Yinliang DiaoLi LiuNuo DengShilei LyuAkimasa Hirata
Published in: Physics in medicine and biology (2023)
Objective&#xD;In protecting human from low-frequency (<100 kHz) exposure, an induced electric field strength is used as a physical quantity for assessment. However, the computational assessment suffers from a staircasing error because of the approximation of curved boundary discretized with cubic voxels. The international guidelines consider an additional reduction factor of 3 when setting the limit of external field strength computed from the permissible induced electric field. Here, a new method was proposed to reduce the staircasing error considering the tensor conductance in human modeling for low-frequency dosimetry.&#xD;Approach&#xD;We proposed a tensor-based conductance model, which was developed on the basis of the filling ratio and the direction of the tissue interface to satisfy the electric field boundary condition and reduce staircasing errors in the target tissue of a voxel human model.&#xD;Main results&#xD;The proposed model was validated using two-layer nonconcentric cylindrical and spherical models with different conductivity contrasts. A comparison of induced electric field strengths with solutions obtained using an analytical formula and finite element method simulation indicated that for a wide range of conductivity ratios, staircasing errors were reduced compared with a conventional scalar-potential finite-difference method. The induced electric field in a simple anatomical head model using our approach was in good agreement with finite element method for exposure to uniform magnetic field exposure and that from coil, simulating transcranial magnetic stimulation.&#xD;Significance&#xD;The proposed tensor-conductance model demonstrated that the staircasing error in an inner target tissue of a voxel human body can be reduced. This finding can be used for the electromagnetic compliance assessment and dose evaluation in electric or magnetic stimulation at low frequencies.&#xD.
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