Predicting New-onset Exertional and Resting Hypoxemia in Fibrotic Interstitial Lung Disease.
Ferhan SaleemChristopher J RyersonNandini SarmaKerri JohannsonVeronica MarcouxJolene FisherDeborah AssayagHelene ManganasNasreen KhalilJulie MorissetIan N GlaspoleNicole GohJustin M OldhamGerard CoxCharlene FellAndrea S GershonAndrew J HalaykoNathan HamblyStacey D LokShane S ShaperaTeresa ToPearce G WilcoxAlyson W WongMartin R J KolbYet Hong KhorPublished in: Annals of the American Thoracic Society (2023)
This clinically applicable risk prediction tool predicted new-onset exertional and resting hypoxemia at six months in the derivation cohort and a diverse validation cohort. Suboptimal GoF in the validation cohort likely reflected overestimation of hypoxemia risk and indicated that the model is not flawed due to underestimation of hypoxemia.