Resistance levels to non-nucleoside reverse transcriptase inhibitors among pregnant women with recent HIV infection in Malawi.
George BelloMatthew KagoliSikhona ChipetaAndrew AuldJoy C-W ChangJoshua R DeVosEvelyn KimJonathan MkungudzaDanielle PayneMichael EliyaRose NyirendaAndreas JahnTaziona MzumaraBernard MvulaSufia DadabhaiIreen NamakhomaYusuf BabayeAmalia GironMichael R JordanSilvia BertagnolioGabrielle O'MalleyNellie Wadonda-KabondoPublished in: Antiviral therapy (2022)
Despite the low number of cases with presumed TDR, our study hints that resistance to NNRTIs was high, above the 10% target for regimen change. Further investigation is needed to establish the exact magnitude of presumed TDR among women recently infected with HIV. These findings support the transition to an integrase inhibitor-based first-line regimen for patients initiating or on ART.
Keyphrases
- antiretroviral therapy
- end stage renal disease
- hiv infected
- ejection fraction
- chronic kidney disease
- hiv positive
- newly diagnosed
- human immunodeficiency virus
- hiv aids
- peritoneal dialysis
- pregnant women
- hepatitis c virus
- hiv testing
- patient reported outcomes
- metabolic syndrome
- skeletal muscle
- density functional theory
- south africa
- pregnancy outcomes
- breast cancer risk