High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition.

Ling-Hui ZengQing-Mei WangLin-Yi FengYu-Dun KeQian-Zi XuAn-Yi WeiChong Zhang Rong-Biao Ying

Published in: OncoTargets and therapy (2019)

High-dose VC inhibits cell migration and invasion of breast cancer cell lines through suppressing EMT. Thus, it may be considered as an anticancer drug candidate for breast cancer patients.

Keyphrases

high dose
epithelial mesenchymal transition
signaling pathway
breast cancer cells
stem cell transplantation
low dose
transforming growth factor
single cell
cell therapy
emergency department
adverse drug
drug induced