Study of the protective effect of ischemic and pharmacological preconditioning on hepatic ischemic reperfusion injury induced in rats.

Afaf Sayed OsmanAhmed H OsmanMahmoud M Kamel

Published in: JGH open : an open access journal of gastroenterology and hepatology (2017)

Ischemic preconditioning and pharmacological preconditioning by lisinopril or verapamil can protect against hepatic ischemia reperfusion probably through inhibition of oxidative stress and neutrophil infiltration. The most potent protection is demonstrated by verapamil treatment.

Keyphrases

cerebral ischemia
ischemia reperfusion injury
oxidative stress
subarachnoid hemorrhage
diabetic rats
blood brain barrier
brain injury
high glucose
heart failure
induced apoptosis
signaling pathway
combination therapy
acute ischemic stroke
stress induced