Changes in Sex Steroids and Relation With Menopausal Complaints in Women Undergoing Risk-reducing Salpingo-oophorectomy.
Lennart J van WindenRavi F M VermeulenVincent van den NoortKatja N GaarenstroomGemma G KenterMonique M A Brood-van ZantenCatharina M KorseMarc van BeurdenHuub H van RossumPublished in: Journal of the Endocrine Society (2022)
Our results suggest that in premenopausal women, decreases in estrogens are related to a decrease in sexual functioning and that in postmenopausal women, testosterone is decreased after RRSO, which indicates that postmenopausal ovaries maintain some testosterone production. Furthermore, in postmenopausal women, a large decrease of testosterone was associated with more menopausal complaints, indicating that future studies investigating testosterone supplementation are warranted.