Comparing Genetic Risk and Clinical Risk Classification in Luminal-like Breast Cancer Patients Using a 23-Gene Classifier.

Chi-Cheng Huang Ting-Hao ChenLiang-Chih LiuChiun-Sheng HuangJi-An LiangYu-Chen HsuChia-Ming HsiehSean-Lin HuangKuan-Hui ShihLing-Ming Tseng

Published in: Cancers (2022)

This study showed that 23-gene classifier can be used to stratify clinically high-risk patients into distinct survival patterns based on genomic risks and displays the potentiality to guide adjuvant chemotherapy. The 23-gene classifier can provide a better estimation of breast cancer prognosis which can help physicians make a better treatment decision.

Keyphrases

copy number
genome wide
end stage renal disease
genome wide identification
primary care
ejection fraction
newly diagnosed
peritoneal dialysis
deep learning
gene expression
risk assessment
transcription factor
decision making
patient reported outcomes
smoking cessation