Hyperthermic Intraperitoneal Chemotherapy-Induced Molecular Changes in Humans Validate Preclinical Data in Ovarian Cancer.
Thanh H DellingerErnest S HanMustafa RaoofByrne LeeXiwei WuHyejin ChoTing-Fang HePeter P LeeMarianne RazaviWinnie S LiangDaniel SchmolzeSaul J PricemanStephen LeeWei-Chien LinJeff F LinMehdi KebriaAmy HakimNora RuelDaphne B StewartEdward W WangBenjamin I PazMark T WakabayashiMihaela C CristeaLorna Rodriguez-RodriguezPublished in: JCO precision oncology (2022)
Distinct transcriptomic signatures identify responders to HIPEC, and preclinical model findings are confirmed for the first time in a human cohort.