Sex bias of females in survival from cancer and infections. Is X the answer?
Abdullah Al EmranStuart J GallagherJessamy C TiffenPeter HerseyPublished in: British journal of cancer (2021)
Major differences in survival of men and women from infectious diseases and cancers have been highlighted by death rates from COVID-19 infections. In cancer, attention has been focussed on differences in gene expression from X chromosomes in men and women with a preponderance of genes involved in immune responses being expressed in women. Important findings have been that some of the genes are important epigenetic regulators that play fundamental roles in immune responses.
Keyphrases
- immune response
- gene expression
- papillary thyroid
- infectious diseases
- dna methylation
- squamous cell
- sars cov
- childhood cancer
- genome wide
- type diabetes
- working memory
- toll like receptor
- squamous cell carcinoma
- pregnant women
- free survival
- transcription factor
- middle aged
- young adults
- pregnancy outcomes
- inflammatory response
- respiratory syndrome coronavirus
- genome wide identification