Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures.

Luhang HanHongmei ZhangAkhilesh KaushalFaisal I RezwanLatha KadalayilWilfried KarmausA John HendersonCaroline L ReltonSusan RingS Hasan ArshadSusan L EwartJohn W Holloway

Published in: Clinical epigenetics (2019)

Adolescent transition is associated with changes in DNA-M at more than 15K CpGs. Identified pathways emphasize the importance of this period of transition on epigenetic state of genes relevant to cell growth and immune system development.

Keyphrases

dna methylation
genome wide
gene expression
young adults
circulating tumor
depressive symptoms
mental health
air pollution
single molecule
cell free
copy number
bioinformatics analysis
genome wide identification