Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.

Guenter FroeschlElmar SaathoffInge KroidlNicole Berens-RihaPetra ClowesLeonard MabokoWeston AssisyaWolfram MwalongoMartina GerhardtElias Nyanda NtinginyaMichael Hoelscher

Published in: Malaria journal (2018)

The longitudinal study showed a significant and relevant decline in the prevalence of P. falciparum infection after introduction of ACT, which could not be explained by potential confounders. The data suggests that artemisinin-based combinations are not only an effective instrument for reduction of immediate morbidity and mortality, but also for reduction of transmission rates.

Keyphrases

combination therapy
plasmodium falciparum
risk factors
big data
risk assessment
human health
climate change
artificial intelligence