Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.
Guenter FroeschlElmar SaathoffInge KroidlNicole Berens-RihaPetra ClowesLeonard MabokoWeston AssisyaWolfram MwalongoMartina GerhardtElias Nyanda NtinginyaMichael HoelscherPublished in: Malaria journal (2018)
The longitudinal study showed a significant and relevant decline in the prevalence of P. falciparum infection after introduction of ACT, which could not be explained by potential confounders. The data suggests that artemisinin-based combinations are not only an effective instrument for reduction of immediate morbidity and mortality, but also for reduction of transmission rates.