Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability.

Tatu Kantonen Laura PekkarinenTomi KarjalainenMarco BucciKari KalliokoskiMerja Haaparanta-SolinRichard AarnioAlex M DickensAnnie von EykenKirsi LaitinenNoora HouttuAnna K KirjavainenSemi HelinJussi HirvonenTapani RönnemaaPirjo NuutilaLauri Nummenmaa

Published in: International journal of obesity (2005) (2021)

These results suggest that the hereditary mechanisms promoting obesity may be partly mediated via insulin, opioid and endocannabinoid messaging systems in the brain.

Keyphrases

type diabetes
insulin resistance
chronic pain
metabolic syndrome
weight loss
pain management
high fat diet induced
weight gain
cerebral ischemia
white matter
adipose tissue
binding protein
cerebral blood flow