Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren's syndrome.
Erika HuijserIris L A BodewesMirthe S LourensCornelia G van Helden-MeeuwsenThierry P P van den BoschDwin G B GrashofHarmen J G van de WerkenAna P LopesJoel A G van RoonPaul L A van DaeleZana BrkicWillem A DikMarjan A VersnelPublished in: Rheumatology (Oxford, England) (2022)
pSS monocytes and pDCs are hyperresponsive to stimulation of the STING pathway, which was not restricted to patients with IFN-I pathway activation.