Usability of rectal swabs for microbiome sampling in a cohort study of hematological and oncological patients.
Lena M BiehlDebora GarzettiFedja FarowskiDiana RingMartin B KoeppelHolger RohdePhilippe SchafhausenBärbel StecherMaria J G T VehreschildPublished in: PloS one (2019)
Deep rectal swabs were shown to be reliable for microbiome sampling and analysis, with practical advantages related to high sampling adherence, easy timing, transport and storage. The relatively high abundance of putative skin commensals in this patient cohort may be of potential interest and should be further investigated. Generally, previous findings on alpha diversity dynamics obtained from stool samples were confirmed.
Keyphrases
- rectal cancer
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- case report
- prostate cancer
- healthcare
- health information
- metabolic syndrome
- soft tissue
- patient reported outcomes
- radical prostatectomy
- risk assessment
- high resolution
- minimally invasive
- climate change
- human health
- patient reported