Encapsulation of curcumin into layered double hydroxides improve their anticancer and antiparasitic activity.
Filiberto Gutiérrez-GutiérrezCecilia Sánchez-JiménezItzia Azucena Rangel-CastañedaGregório Guadalupe Carbajal ArízagaAdriana Macaria Macías-LamasAraceli Castillo-RomeroKarina Jeanette Parra-SaavedraPublished in: The Journal of pharmacy and pharmacology (2020)
Layered double hydroxides are good vehicles to improve stability, resistance to degradation of CUR, also they are useful to improve solubility, provide a controlled release and improve the cytotoxic activity. Additionally, it was shown that the composition of the M+2 cation of LDH affects its properties and structure and that this directly influences its biological activity. The findings are important to select the composition of the encapsulation vehicle for a specific activity.
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