Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.

Till SeiboldtConstantia ZeiserDuy NguyenSimay CelikyürekliSonja HerterSara NajafiAlexandra Stroh-DegeChris MeulenbroeksNorman MackRabia Salem-AltintasFrank WestermannMatthias SchlesnerTill MildeMarcel KoolTim Holland-LetzMeike VoglerHeike PeterzielOlaf Witt Ina Oehme

Published in: British journal of cancer (2024)

and NB cells for apoptosis, triggered by navitoclax cotreatment.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
pi k akt
oxidative stress
transcription factor
signaling pathway