The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study.

Fangshi XuYibing GuanLi XuePeng ZhangMingrui LiMei GaoTie Chong

Published in: Cancer medicine (2021)

SLC7A11 not only deeply influences RCC prognosis and TIM, but also promotes RCC progression by inhibiting ferroptosis and inducing metabolic reprogramming. In addition, SLC7A11 weakly affects the therapeutic effect and sensitivities of multiple chemotherapy and targeted drugs.

Keyphrases

renal cell carcinoma
cell death
signaling pathway
genome wide
locally advanced
copy number
squamous cell carcinoma
drug delivery
rectal cancer