Comparative Evaluation of Diagnostic Performance: Standard E TB Feron ELISA vs QuantiFERON-TB Gold Plus for Latent Tuberculosis Infection Detection in Diverse Risk Groups in Bangladesh.

Mohammad Khaja Mafij UddinAshabul IslamMaha Sultana JabinTahmina AlamSalwa KhairJannatul FerdousRumana NasrinSyed Mohammad Mazidur RahmanStephane PouzolJonathan HoffmannSayera Banu

Published in: Infection and drug resistance (2024)

We found a substantial agreement (Cohen's kappa of 0.71) between TBE and QFT-Plus in detecting LTBI across different groups, suggesting its potential as a cost-effective diagnostic tool. Implementation of TBE in routine clinical practice could increase accessibility to LTBI diagnosis, facilitating the timely initiation of preventative therapy, and leading to a reduction of active TB incidence.

Keyphrases

mycobacterium tuberculosis
clinical practice
pulmonary tuberculosis
primary care
nuclear factor
healthcare
risk factors
quality improvement
emergency department
stem cells
mesenchymal stem cells
hiv aids
loop mediated isothermal amplification
toll like receptor
silver nanoparticles