Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling.

Jianxiong JiRan XuKaikai DingGuoqing BaoXin ZhangBin HuangXinyu WangAurora MartinezXiuying WangGang LiHrvoje MileticFrits ThorsenRolf BjerkvigLei XiangBo HanAnjing ChenXingang LiJian Wang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our results implicated SChLAP1 as a driver of GBM growth as well as a potential therapeutic target in treatment of the disease.

Keyphrases

long noncoding rna
endothelial cells
signaling pathway
oxidative stress
lps induced
nuclear factor
induced pluripotent stem cells
pi k akt
immune response
inflammatory response
cell proliferation
combination therapy
replacement therapy
toll like receptor