Real-world analysis of clinicopathological characteristics, survival rates, and prognostic factors in patients with melanoma brain metastases in China.
Yang WangBin LianLu SiZhiHong ChiXiNan ShengXuan WangLiLi MaoBiXia TangSiMing LiXieQiao YanXue BaiLi ZhouChuanliang CuiJun GuoPublished in: Journal of cancer research and clinical oncology (2021)
Our findings depict clinical characteristics and prognostic factors of MBM in the East Asian population, suggesting the mucosal subtype as an adverse prognostic and predictive factor for patients with MBM. For BRAF mutation patients with MBM, first-line BRAF/MEK inhibitor therapy may bring a potential survival benefit compared to first-line anti-PD-1 therapy.