Time-Dependent Displacement of Commensal Skin Microbes by Pathogens at the Site of Colorectal Surgery.
Jennifer Holder-MurrayAndrew YehMatthew B RogersBrian FirekBrandon MahlerDavid MedichJames CelebrezzeMichael J MorowitzPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
We observed reproducible perioperative changes in the skin microbiome following surgery. The low incidence of SSIs in this cohort precluded analysis of associations between dysbiosis and infection. We postulate that real-time monitoring of the skin microbiome could provide actionable findings about the pathogenesis of SSIs.