Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir.

Wenyu Yang Wen Yao MakAmanda GweeMeng GuYue WuYufei Shi Qingfeng He Xiao-Qiang XiangBing HanXiao Zhu

Published in: Pharmaceutics (2023)

exceeding the exposure thresholds for toxicity (120 mg·h/L) in 51.24% adults. (4) Conclusions: Dosing regimens of ganciclovir and valganciclovir should be adjusted according to body size and renal function. This model repository has a broad range of potential applications in MIPD.

Keyphrases

oxidative stress
climate change
human health