Universal digital high-resolution melting for the detection of pulmonary mold infections.
Tyler GoshiaApril AralarNathan P WiederholdJeffrey D JenksSanjay R MehtaAprajita KarmakarMonish E SAnkit SharmaHaoxiang SunRefilwe KebadirengPhilip Lewis WhiteMridu SinhaMartin HoeniglStephanie I FraleyPublished in: Journal of clinical microbiology (2024)
Improvements in diagnostics for invasive mold infections are urgently needed. This work presents a new molecular detection approach that addresses technical and workflow challenges to provide fast pathogen detection, identification, and quantification that could inform treatment to improve patient outcomes.