Bioinspired Suspended Sensing Membrane Array with Modulable Wedged-Conductive Channels for Crosstalk-Free and High-Resolution Detection.
Haixuan LuoXiaoliang ChenSheng LiJinbin XuXiangming LiHongmiao TianChunhui WangBo LiManman ZhangBai SunJuan HeJinyou ShaoPublished in: Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
High spatial-resolution detection is essential for biomedical applications and human-machine interaction. However, as the sensor array density increases, the miniaturization will lead to interference between adjacent units and deterioration in sensing performance. Here, inspired by the cochlea's sensing structure, a high-density flexible pressure sensor array featuring with suspended sensing membrane with sensitivity-enhanced customized channels is presented for crosstalk-free and high-resolution detection. By imitating the basilar membrane attached to spiral ligaments, a sensing membrane is fixed onto a high-stiffness substrate with cavities, forming a stable braced isolation to provide an excellent crosstalk-free capability (crosstalk coefficient: 47.24 dB) with high-density integration (100 units within 1 cm 2 ). Similar to the opening of ion channels in hair cells, the wedge-type expansion of the embedded cracks introduced by stress concentration structures enables a high sensitivity (0.19 kPa -1 ) and a large measuring range (400 kPa). Finally, it demonstrates promising applications in distributed displays and the condition monitoring of medical-surgical intubation.
Keyphrases
- high density
- high resolution
- loop mediated isothermal amplification
- label free
- endothelial cells
- real time pcr
- induced apoptosis
- mass spectrometry
- cardiac arrest
- magnetic resonance imaging
- cell death
- deep learning
- gold nanoparticles
- cell cycle arrest
- single molecule
- sensitive detection
- quantum dots
- stress induced
- reduced graphene oxide
- neural network