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Autologous Serum Eye Drops Diluted with Cyclosporine A 0.05% and Sodium Hyaluronate 0.1%: An Experimental Comparative Study.

Rajan SharmaAshok SharmaVandita KakkarKomal SainiJanardhana P BalakrishnaVerinder S Nirankari
Published in: Current eye research (2024)
Two test combinations (AS + CsA, AS + SH) showed stable growth factors (EGF, TGF-β) and good anti-inflammatory property against pro-inflammatory markers. Also, the 2 combinations were found safe on cultured limbal epithelial cells. The novel combination of autologous serum in CsA may provide added benefit in dry eye disease (DED) through their combined anti-inflammatory and epitheliotropic effects.
Keyphrases
  • anti inflammatory
  • bone marrow
  • cell therapy
  • platelet rich plasma
  • growth factor
  • stem cells
  • mesenchymal stem cells