The epidemiology and estimated etiology of pathogens detected from the upper respiratory tract of adults with severe acute respiratory infections in multiple countries, 2014-2015.
Jennifer L MiluckyTracy PondoChristopher J GregoryDanielle IulianoSandra S ChavesJohn McCrackenAdel MansourYuzhi ZhangMohammad Abdul AleemBernard WolffBrett WhitakerToni WhistlerClayton OnyangoMaria Renee LopezNa LiuMohammed Ziaur RahmanNong ShangJonas WinchellMalinee ChittaganpitchBarry FieldsHerberth Giovanni Maldonado BrionesZhiping XieStephen LindstromKatherine Sturm-RamirezJoel MontgomeryKai-Hui WuChris A Van Benedennull nullPublished in: PloS one (2020)
Use of multi-pathogen diagnostics and modeling enabled attribution of etiology in most adult SARI patients, despite frequent detection of multiple pathogens in the upper respiratory tract. Seasonal flu vaccination and development of RSV vaccine would likely reduce the burden of SARI in these populations.