Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.

Shervin AssassiXuan WangGuocai ChenEllen GoldmuntzLynette Keyes-ElsteinJun YingPaul K WallaceJacob TurnerW Jim ZhengVirginia PascualJohn VargaMonique E HinchcliffChiara BellocchiPeter McSweeneyDaniel E FurstRichard A NashLeslie J CroffordBeverly WelchAshley PinckneyMaureen D MayesKeith M Sullivan

Published in: Annals of the rheumatic diseases (2019)

HSCT contrary to conventional treatment leads to a significant 'correction' in disease-related molecular signatures.

Keyphrases

systemic sclerosis
stem cell transplantation
interstitial lung disease
high dose
genome wide
bone marrow
single molecule
cell therapy
rheumatoid arthritis
stem cells
mesenchymal stem cells
combination therapy