Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk.
Xuan ZhouQian XiaoFangyuan JiangJing SunLijuan WangLili YuYajing ZhouJianhui ZhaoHan ZhangQiqiang HeMaria N TimofeevaAthina SpiliopoulouInes Mesa-EguiagaraySusan M FarringtonPhilip J LawRichard S HoulstonKefeng DingMalcolm G DunlopEvropi TheodoratouXue LiPublished in: British journal of cancer (2023)
Our study confirms the significant association between tobacco smoking, DNA methylation and CRC risk and yields a novel insight into the pathogenic effect of tobacco smoking on CRC risk.