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An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22).

Mishi BhushanKirthi R Kumar
Published in: Clinical case reports (2021)
First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1-RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation.
Keyphrases
  • chronic lymphocytic leukemia
  • case report
  • transcription factor
  • genome wide
  • copy number
  • genome wide identification
  • dna methylation
  • genome wide analysis