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Targeting CXCR4/CXCL12 axis via [ 177 Lu]Lu-DOTAGA.(SA.FAPi) 2 with CXCR4 antagonist in triple-negative breast cancer.

Guangfa BaoZiqiang WangLuoxia LiuBuchuan ZhangShuang SongDongdong WangSiyuan ChengEu-Song MoonFrank RoeschJun ZhaoBo YuXiaohua Zhu
Published in: European journal of nuclear medicine and molecular imaging (2024)
and AMD3100 is a feasible treatment against TNBC with minimal toxicity in main organs.
Keyphrases
  • cell migration
  • oxidative stress
  • cancer therapy
  • combination therapy
  • drug delivery