Proteomic and phenotypic characteristics of memory-like natural killer cells for cancer immunotherapy.

Helena Arellano-BallesteroAgnieszka ZubiakChris DallyKim OrchardAljawharah AlrubayyiXenia CharalambousMelina MichaelRobert TorranceTrinity EalesKushal DasMaxine G B TranMay SabryDimitra PeppaMark W Lowdell

Published in: Journal for immunotherapy of cancer (2024)

NK cell "memory" is a physiological state associated with resistance to MHC-mediated inhibition, increased metabolic function, mitochondrial fitness and avidity to NK-resistant target cells.

Keyphrases

nk cells
natural killer cells
induced apoptosis

working memory
oxidative stress

cell cycle arrest
physical activity

body composition
endoplasmic reticulum stress