The role of immunoglobulin E and mast cells in hypertension.
Weipeng GeXiaoxiao GuoXiaomin SongJunling PangXuan ZouYonglin LiuYongliang NiuZhengqing LiHongmei ZhaoRan GaoJiangning LiuPublished in: Cardiovascular research (2022)
Our findings reveal that IgE contributes to the pathogenesis of hypertension, at least partially through activating the IgE-FcεR1 signalling in MCs. Thus, IgE may represent a new therapeutic target for IgE-mediated hypertension.