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The dynamic changes in the number of uterine natural killer cells are specific to the eutopic but not to the ectopic endometrium in women and in a baboon model of endometriosis.

Josephine A DruryKirstin L ParkinLucy CoyneEmma GiulianiAsgerally T FazleabasDharani K Hapangama
Published in: Reproductive biology and endocrinology : RB&E (2018)
The dynamic increase in the percentage of uNK cells in the secretory phase is preserved in the endometrium of women with endometriosis. The low number of uNK cells in human and baboon ectopic lesions may be due to their exaggerated reduction in hormonal responsiveness (progesterone resistance).
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • natural killer cells
  • polycystic ovary syndrome
  • endothelial cells
  • signaling pathway
  • cell proliferation
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • pi k akt