A Holistic Approach to Risk for Early Kidney Injury in Indigenous Youth With Type 2 Diabetes: A Proof of Concept Paper From the iCARE Cohort.
Allison B DartBrandy WicklowTom D Blydt-HansenElizabeth A C SellersSayma MalikDan ChateauAtul SharmaJonathan M McGavockPublished in: Canadian journal of kidney health and disease (2019)
Albuminuria is highly prevalent in Indigenous youth with T2D. This preliminary analysis supports a theoretical framework linking glycemic control, hypertension, and inflammation, potentially mediated by psychological factors with albuminuria. These data support the need for more holistic models of evaluation and care for youth with T2D and multifactorial interventions to prevent complications.
Keyphrases
- glycemic control
- physical activity
- mental health
- young adults
- type diabetes
- blood pressure
- healthcare
- oxidative stress
- blood glucose
- palliative care
- risk factors
- electronic health record
- weight loss
- quality improvement
- insulin resistance
- big data
- adipose tissue
- depressive symptoms
- artificial intelligence
- arterial hypertension