Cystathionine β-synthase and methylenetetrahydrofolate reductase mutations in Mexican individuals with hyperhomocysteinemia.
Anahi Guadalupe Figueroa-TorresLisneth Osiris Matias-AguilarErika Coria-RamirezEdmundo Bonilla-GonzalezHumberto Gonzalez-MarquezIsabel Ibarra-GonzalezJose Rubicel Hernandez-LopezJesus Hernandez-JuarezVictor Manuel Dominguez-ReyesIrma Isordia-SalasAbraham Salvador Majluf-CruzPublished in: SAGE open medicine (2020)
There is an association between fasting and post-oral methionine load plasma Hcy concentrations with the allelic frequencies of the polymorphisms C669T, 844ins68, and C1080T of the cystathionine β-synthase and C667T of the methylenetetrahydrofolate reductase in healthy Mexican individuals. As compared with individuals with normal fasting or post-oral methionine load Hcy plasma levels, only C1080T was significantly associated with hyperhomocysteinemia.