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The genetic diversity of human papillomavirus types from the species Gammapapillomavirus 15: HPV135, HPV146, and HPV179.

Lea HošnjakBoštjan J KocjanBranko PiršKatja SemeMario Poljak
Published in: PloS one (2021)
HPV179, HPV135, and HPV146 have a mucocutaneous tissue tropism and are associated with sporadic infections in immunocompromised and immunocompetent individuals. Because the majority of mutations were found outside the major functional domains of the respective LCRs, we assume that HPV179, HPV135, and HPV146 genetic variants pathogenically do not differ from their prototypes. In addition, no association was found between specific HPV179, HPV135, and HPV146 genetic variants and anatomical sites of infection and/or specific neoplasms.
Keyphrases
  • high grade
  • cervical cancer screening
  • genetic diversity
  • early onset
  • amyotrophic lateral sclerosis