Perianal Paget's disease as spread from non-invasive colorectal adenomas.
Danielle A HutchingsAnnika WindonNaziheh AssarzadeganKevan J SalimianLysandra VoltaggioElizabeth A MontgomeryPublished in: Histopathology (2020)
Similar to its mammary analogue, secondary perianal Paget's disease may arise in association with invasive and/or in-situ colorectal lesions. Although the latter is an uncommon presentation of a recognised rare disease, knowledge of this phenomenon is important to forestall overdiagnosis of invasion and potential overtreatment. The clinical course is variable, such that close follow-up is required.
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