Dopaminergic function in spinocerebellar ataxia type 6 patients with and without parkinsonism.

Yoshihiko HorimotoEmi HayashiYoshihiro ItoAkihiko IidaYoji GotoShigenori KatoKenji OkitaTetsuharu KakoChikako SatoToshihisa TajimaAki InagakiKazuya NokuraHiroaki HibinoNoriyuki MatsukawaKazuo YamadaHidehiro Kabasawa

Published in: Journal of neurology (2020)

The pathology of SCA6 may not be restricted to the cerebellum, but may also be distributed across various regions, including in both presynaptic and postsynaptic dopaminergic neurons to some degree. Patients with SCA6 may show apparent parkinsonism after the progression of neurodegeneration.

Keyphrases

parkinson disease
drug induced
spinal cord
early onset
diffusion weighted imaging
deep brain stimulation
magnetic resonance imaging
computed tomography
neural network
spinal cord injury