Plasma low-molecular-weight thiol/disulphide homeostasis as an early indicator of global and focal cerebral ischaemia.

Alexander Vladimirovich IvanovValery Vasil'evich AlexandrinAlexander Alexandrovich PaltsynKsenya Alexandrovna NikiforovaEdward Danielevich VirusBoris Petrovich LuzyaninMarina Yurievna MaksimovaMikhail Aleksanrovich PiradovAslan Amirkhanovich Kubatiev

Published in: Redox report : communications in free radical research (2017)

These results suggest that plasma low-molecular-weight thiols are actively involved in oxidation reactions at early stages of cerebral ischaemia; therefore, their reduced forms or redox state may serve as a sensitive indicator of acute cerebrovascular insufficiency.

Keyphrases

subarachnoid hemorrhage
liver failure
cerebral ischemia
respiratory failure
brain injury
hydrogen peroxide
drug induced
aortic dissection
intensive care unit
cerebral blood flow
nitric oxide