Atomized inhalation of Icaritin reduces airway inflammation and remodeling in asthmatic mice.

Yintong HeJian CuiBo XiaoLixia HouZhimei LiHuiqing ZuoYutong HeDong Yao

Published in: The Journal of asthma : official journal of the Association for the Care of Asthma (2024)

Nebulized inhalation of ICT can effectively inhibit airway inflammation in asthmatic mice, improve airway remodeling, and reduce airway hyperresponsiveness, with effects similar to those of hormones. It may serve as a potential candidate used as a hormone replacement asthma treatment.

Keyphrases

lung function
high fat diet induced
chronic obstructive pulmonary disease
insulin resistance
air pollution
wild type
adipose tissue
skeletal muscle
replacement therapy